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CNN —Using acetaminophen, the active ingredient in Tylenol, during pregnancy was not associated with increased risk of autism, ADHD or intellectual disability in children, a new study found. “This is a very extensive and well-designed study that found no association between acetaminophen use and neurodevelopmental impairment, including autism and ADHD,” he said. For example, the study found that parents who have neurodevelopmental disorders — which have strong heritability — are also more likely to use pain medications, like acetaminophen, during pregnancy. This relationship might make it seem like children who are exposed to acetaminophen during pregnancy are more likely to develop neurodevelopmental disorders, when, in fact, their increased risk is due to genetics, according to the study. The study found significant differences between birthing parents with higher acetaminophen use and those with lower or no use.
Persons: , ” Dr, Eric Brenner, ” Brenner, , Brenner, Dr, Sanjay Gupta, judiciously, Yalda Afshar Organizations: CNN, Karolinska Institute, Drexel University, Duke University, Food and Drug Administration, European Medicines Agency, Get CNN, CNN Health, FDA, David Geffen School of Medicine, UCLA Locations: Sweden
Take Dennis and Douglas. In high school, they were so alike that friends told them apart by the cars they drove, they told researchers in a study of twins in Virginia. Most of their childhood experiences were shared — except that Dennis endured an attempted molestation when he was 13. At 18, Douglas married his high school girlfriend. Why do twins, who share so many genetic and environmental inputs, diverge as adults in their experience of mental illness?
Persons: Dennis, Douglas Organizations: University of Iceland, Karolinska Institutet Locations: Virginia, Sweden
The woman behind the next big thing in cancer treatment
  + stars: | 2024-02-20 | by ( Katie Hunt | ) edition.cnn.com   time to read: +12 min
Christine Olsson/AFP/Getty ImagesWu’s research focused on small mutations in cancer tumor cells. However, in many cases, cancer vaccines have failed to live up to their promise — largely because the right target hasn’t been found. “This is a fantastic discovery.”By sequencing DNA from healthy and cancer cells, Wu and her team identified a cancer patient’s unique tumor neoantigens. More work is needed before they are a viable treatment options for many cancer patients. To show that these type of cancer vaccines work, much larger randomized control trials are needed.
Persons: Catherine Wu, Boston’s Dana, , , Wu, Lendahl, Dr Patrick Ott, Sam Ogden, Honjo, James Allison, Tasuku Honjo, James P Allison, Christine Olsson, ” Hans, Gustaf Ljunggren, Matt Stone, “ I’m, ” Wu, ” Lendahl, you’ve, It’s, ” Barbara Brigham, BioNTech, ” CNN’s Brenda Goodman Organizations: CNN, Farber Cancer Institute, Royal Swedish Academy of Sciences, Karolinska, Getty, US Food and Drug Administration, FDA, MediaNews, Boston Herald, Merck, Moderna, , Covid Locations: Sweden, BioNTech, Rome
By Ernie Mundell HealthDay ReporterHealthDayFRIDAY, Feb. 9, 2024 (HealthDay News) -- Is 'practice makes perfect' true for the male erection, too? The key seemed to lie in connective tissue cells called fibroblasts. So, "an increased frequency of erections leads to more fibroblasts that enable erection," he said. The opposite also appeared to be true: "A decreased frequency results in fewer of these cells," Göritz said. "This is not something we have shown in our study, so it is a bit speculative, but a reasonable interpretation is that it gets easier if you have regular erections,” Göritz said.
Persons: Ernie Mundell, erections, , Eduardo Guimaraes, Christian Göritz, Göritz, Guimaraes, It’s, ” Göritz Organizations: Karolinska Institute, Karolinska, National Institute of Diabetes Locations: Stockholm, Swedish
Viagra, Cialis Plus a Heart Med Could Be a Dangerous Combo
  + stars: | 2024-01-15 | by ( Jan. | At A.M. | ) www.usnews.com   time to read: +3 min
By Dennis Thompson HealthDay Reporter(HealthDay)MONDAY, Jan. 15, 2024 (HealthDay News) -- Taking nitrates for heart problems alongside erectile dysfunction drugs like Viagra or Cialis could be a prescription for trouble, a new study warns. “Physicians are seeing an increase of requests for erectile dysfunction drugs from men with cardiovascular diseases,” said senior researcher Dr. Daniel Peter Andersson, an associate professor at the Karolinska Institute in Sweden. Among those men, more than 5,700 also had been prescribed an erectile dysfunction drug. The data revealed that men taking both drugs had an overall higher risk of death, as well as of heart attack, heart failure and other major cardiovascular events. Few events occurred within 28 days of men receiving an erectile dysfunction drug, indicating that there is low immediate risk, researchers said.
Persons: Dennis Thompson, Jan, , Daniel Peter Andersson, , ” Andersson, Glenn Levine, Levine Organizations: American College of Cardiology, , Karolinska Institute, American, of Cardiology, Baylor College of Medicine, Texas Heart Institute Locations: Sweden, Levitra, Houston
Strength training, whether performed with weights, bands, machines or your own body weight, is important for your long-term health. In the same study, nearly 60% of participants said they did no strength training at all. Exercise researcher Dr. Tommy Lundberg, author of “The Physiology of Resistance Training,” says strength training is most important for people older than age 65. CNN: Why is strength training important for good health? Resistance training is the only means to effectively maintain or even increase your muscle mass.
Persons: Martin Puddy, Tommy Lundberg, , Eva Malm, Tommy Lundberg Lundberg, Lundberg, Darrin Klimek, it’s, It’s, Melanie Radzicki McManus Organizations: CNN, US Centers for Disease Control, American, of Preventive, National Health, Karolinska Institute, Resistance, Bank, Getty Locations: Solna, Sweden
CNN —Scientists may be closer to understanding the culprit behind the consumption of red wine causing headaches for some people, according to new research. A flavonol naturally occurring in red wines may interfere with the body’s ability to metabolize alcohol, causing an accumulation of toxins that can lead to swift headaches, suggests the study published Monday in the journal Scientific Reports. Using lab tests, the authors found that a derivative of quercetin — quercetin glucuronide — inhibited the enzyme variant. What’s next in the study of red wine headachesThe authors plan to test their hypothesis in a small clinical trial of people who develop these headaches, by comparing red wines with high amounts of quercetin with those that have little. In some cases, it can be four to five times higher.”As a result, you may have better luck with cheaper red wines or with white wines, which have a lower flavonol content overall, according to the study.
Persons: , Andrew Waterhouse, Waterhouse, imbibing, Apramita Devi, , Jonas Spaak, Vasilis Vasiliou, What’s, ” Spaak Organizations: CNN —, University of California, UC Davis, Karolinska Institute, Yale University Locations: Davis, East, Stockholm, Sweden, Napa
And I told her that many, many scientists work very, very hard," Kariko added. BioNTech said in June that about 1.5 billion people across the world had received its mRNA shot, co-developed with Pfizer (PFE.N). [1/11]Katalin Kariko and Drew Weissman win the 2023 Nobel Prize in Physiology or Medicine at the Karolinska Institute in Stockholm, Sweden October 2, 2023. The medicine prize kicks off this year's Nobel awards with the remaining five to be unveiled in coming days. The prizes, first handed out in 1901, were created by Swedish dynamite inventor and wealthy businessman Alfred Nobel.
Persons: Weissman, Katalin Kariko, Drew Weissman, Kariko, BioNTech, Rickard Sandberg, Susan Francia, immunologist, , Sir Andrew Pollard, Alfred Nobel, Swede Svante Paabo, Alexander Fleming, Karl Landsteiner, Niklas Pollard, Johan Ahlander, Ludwig Burger, Terje Solsvik, Andrew Cawthorne Organizations: Medicine, Nobel, Sweden's Karolinska Institute, University of Szeged, University of Pennsylvania, Pfizer, Karolinska Institute, TT News Agency, REUTERS Acquire, Boston University, Oxford University, AstraZeneca, Moderna, Thomson Locations: STOCKHOLM, COVID, Hungary, Pennsylvania, Szeged, U.S, Stockholm, Sweden, Frankfurt, Krisztina, Budapest, Oslo
Things to Know About the Nobel Prizes
  + stars: | 2023-09-30 | by ( Associated Press | Sept. | At A.M. | ) www.usnews.com   time to read: +6 min
Here are some things to know about the Nobel Prizes:AN IDEA MORE POWERFUL THAN DYNAMITEPolitical Cartoons View All 1190 ImagesThe Nobel Prizes were created by Alfred Nobel, a 19th-century businessman and chemist from Sweden. Though Nobel purists stress that the economics prize is technically not a Nobel Prize, it’s always presented together with the others. The Nobel Prizes project an aura of being above the political fray, focused solely on the benefit of humanity. The Norwegian Nobel Committee is an independent body that insists its only mission is to carry out the will of Alfred Nobel. To date, 60 women have won Nobel Prizes, including 25 in the scientific categories.
Persons: Alfred Nobel, Dynamite, , it’s, Nobel, Barack Obama, Liu Xiaobo, Albert Einstein, Mother Teresa, Jean, Paul Sartre, Le Duc Tho, Henry Kissinger, Ales Bialiatski, that’s Organizations: STOCKHOLM, Karolinska Institute, Nobel Foundation, U.S, Royal Swedish Academy of Sciences Locations: Scandinavia, Stockholm, Oslo, Swedish, Sweden, NORWAY, Norway, Norwegian, Beijing, China, Ukraine, Russia, Europe, North America
In the past few months alone, researchers have linked Neanderthal DNA to a serious hand disease, the shape of people's noses and various other human traits. Research shows some African populations have almost no Neanderthal DNA, while those from European or Asian backgrounds have 1% to 2%. For example, Neanderthal DNA has been linked to auto-immune diseases like Graves’ disease and rheumatoid arthritis. The list goes on: Research has linked Neanderthal genetic variants to skin and hair color, behavioral traits, skull shape and Type 2 diabetes. Researchers found the skulls of domesticated dogs in Homo sapiens sites much further back in time than anyone had found before.
Persons: We’re, , Mary Prendergast, Hugo Zeberg, Svante Paabo, Zeberg, It's, Graves, Homo sapiens, Chris Stringer, , Rick Potts, Paabo, ” Zeberg, Raghavan, Potts, Denisovans, sapiens, Eleanor Scerri, Prendergast, Janet Young, Pat Shipman, John Hawks Organizations: Rice University, Karolinska, Research, Smithsonian Institution, University of Chicago, Germany’s Max Planck Institute, Geoanthropology, Canadian Museum, University of Wisconsin -, Associated Press Health, Science Department, Howard Hughes Medical Institute’s Science, Educational Media Group, AP Locations: Sweden, Melanesia, New Guinea, Fiji, Africa, Europe, Asia, London, Eurasia, Germany’s, University of Wisconsin - Madison
Menopause is considered early when it occurs before age 45, which will happen in 5% to 10% of women, Yang said. Early menopause is concerning because of the shortened reproductive years, but also because of links to other health concerns, she added. A 2010 study found that women who experience early menopause are at an increased risk for overall mortality, including cardiovascular diseases, osteoporosis and neurological diseases. How are PMS and early menopause connected? Women also need to know that there are ways to manage early menopause and the bothersome hot flashes, she said.
Persons: , Yihui Yang, Yang, Stephanie Faubion, Faubion, , Donghao Lu, ” Faubion, Elizabeth Bertone, Johnson, Organizations: CNN, Karolinska Institutet, Mayo Clinic Center, Women’s Health, PMDs, Karolinska, University of Massachusetts Amherst, American College of Obstetricians, Women’s, US Department of Health, Human Services Locations: Sweden
And the truth is that the benefits of a good vacation can be felt even before the trip begins. The “other stress” – the one that has negative connotations for everyone – is chronic stress. Alexander Spatari/Moment RF/Getty ImagesThe main thing that a good vacation can do for our mental health is precisely to reduce chronic stress levels. Therefore, knowing that our vacation is coming increases the dopamine levels in our brain and gives us that feeling of pleasure. Be that as it may, good vacations are good for us.
Persons: , Alexander Spatari, Juan Pérez Fernández, Roberto de la Torre Organizations: CNN, Getty, University of Vigo, Roberto de la Torre Martínez, Department, Neuroscience, Karolinska Institute Locations: daydreaming, CINBIO, Spain, Sweden
New research is exploring another dimension to the puzzle of how people experience this infection: genes. Hollenbach says it’s the job of HLA molecules to present pieces of proteins to the immune system so they can be recognized if they’re ever encountered again. The researchers then took a closer look at this group to see if there were any similarities in the genes that coded for their HLA molecules, and there were. So folks with these HLA molecules likely already had some preexisting immunity against SARS-CoV2 and were able to clear the virus before it caused symptoms, Hollenbach said. Genes, Zeberg said, are likely only one part of reason why someone develops long Covid, and there are probably a slew of genes involved.
Persons: Covid, , Jill Hollenbach, Hollenbach, they’re, , ” Hollenbach, they’d, it’s, Gene, Dr, Sanjay Gupta, Hugo Zeberg, Zeberg Organizations: CNN, University of California, San Francisco’s Weill, for Neurosciences, Karolinska Institute, Get CNN, CNN Health, Karolinska . Genes Locations: San, Stockholm, FOXP4
Interbreeding with Homo sapiens helps to explain why millions can't straighten their fingers. There is also a Neanderthal gene variant that increases the risk of somebody dying from COVID-19. The study evidences that "intermingling" from Neanderthals and our Homo sapiens ancestors is consequential in examining the prevalence of certain diseases, researchers said. No more than 7% of the human genome is unique to Homo sapiens, according to a study published in the journal Science Advances. Brain development and function are what sets Homo sapiens apart, experts explained.
Persons: sapiens, , Hugo Zeberg, Nikola Solic, Zeberg Organizations: Service, British Society for Surgery, Karolinska Institute, Times Locations: COVID, Europe, Finland, Africa, Sweden, Asia
Daniel Erichsen, founder of the Sleep Coach School Daniel ErichsenDaniel Erichsen spent about a decade as a sleep doctor, primarily seeing patients who were struggling with sleep apnea and insomnia. According to market research firm Imarc, the global insomnia market will hit $5.1 billion this year and climb to $6.1 billion by 2028. Other apps, including some backed by venture capital firms, promote cognitive behavioral therapy for insomnia, or CBT-I. That therapy is meant to change the way people think about sleep and incorporates behavior changes like sleep restriction and stimulus control. Kendall's message, which mirrors much of Erichsen's teachings, is that sleep is simple, but insomnia makes it seem complex.
A 2020 study, for example, found using marijuana before entering the hospital for a surgical procedure made pain during recovery significantly worse. In fact, the optimistic attitude generated by a placebo can be powerful enough to affect study results dramatically. A unique part of the study looked at the role of news and social media for the placebo effect in cannabis clinical trials, Jensen said. Researchers found positive media coverage after each of the cannabis clinical trials, even when the study results were less than spectacular, she said. “I don’t think you can explain the placebo effect or blame it on social media.
A constant influx of bad news — pandemic, shootings, inflation, natural disasters, political turmoil — can feel, at best, soul-crushing. Now, a new study from Spain confirms the negative toll constantly being plugged into the news cycle can take. Others note that there's only so much negative news coverage a person can take before it affects their mental health. The study found that those who avoided "too much stressful news" had fewer symptoms of anxiety and depression. The research also tracked whether the participants got Covid during the study period.
Eli Lilly logo is shown on one of the company's offices in San Diego, California, U.S., September 17, 2020. Nearly all Alzheimer's drugs, including those targeting amyloid, have stumbled in trials. Late-stage data on gantenerumab is expected by the fourth quarter, Roche said in a statement, saying it was encouraged by the lecanemab data. Results of a key late-stage trial testing the drug are anticipated by mid-2023. AMYLOID HYPOTHESISSome researchers, including Frederiksen, are cautiously optimistic about the impact the Biogen, Eisai data has on the likelihood of success for the other two drugs in development.
Cristina Dumitraș este una dintre tinerii care au luat 10 pe linie la examenul de bacalaureat din acest an. Eleva spune că prima persoană care a felicitat-o a fost mama dânsei: „Ambele eram foarte emoționate de vestea cea mare. Andreea Stici, tânăra care a luat patru de 10 la BAC. Laura Gherman, tânăra care a luat patru de 10 la BAC. Evelina Nuca, tânăra care a luat patru de 10 la BAC.
Persons: Cristina Dumitraș, Mihai Viteazul, Cristina, Cristina confesează, Andreea Stici, Laura Gherman, Dana Țopa, Dan Negru, Vlada Caraman, Mădălina Costețchi, Cojocaru Irina, Eduard Mititiuc Organizations: Cambridge, Groningen University, Elevilor, Evelina, Vlada Locations: Chișinău, România, universitatea, Republica Moldova, Suedia, Olanda, Groningen
Пожилой возраст может способствовать развитию жировой болезни печени, но чаще всего ее причиной являются нездоровые привычки питания, ожирение и другие признаки метаболического синдрома. Ученые пришли к выводу, что клинические испытания на людях будут полезны для определения того, будет ли пищевой нитрат полезным для лечения и профилактики жировой болезни печени. Будучи одним из продуктов питания, который ученые назвали отличным для вашей печени, она не только легкодоступна в магазинах и недорога, учитывая ее питательную пользу, но ее также легко выращивать. Кроме того, по данным Института Линуса Полинга, в одной чашке содержится 8,2 миллиграмма хлорофилла, что способствует заживлению ран и, что более важно, помогает предотвратить заболевание печени. Он может также быть вызван НАЖБП (у которой в названии указывается, что это «неалкогольное» заболевание печени), а также ожирением и гепатитом.
Persons: Маттиас Карлстрем, Карлстрем, функцииНикто, Руккола, Эллиот Таппер, Гюнтер Кунле Organizations: Karolinska, Medical, Today, Molecular Nutrition, Food Research, NPR, Национальный институт здравоохранения, Слушания Национальной Академии Наук (), Каролинский институт, Институт Линуса Полинга, НАЖБП, Национальный институт диабета, Национальный институт здравоохранения (НИЗ), Университет Рединга Locations: США, Швеция, Великобритания
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